The authors distinguish between weight loss and weight loss maintenance and detail the extraordinary metabolic complexities, from adipose tissue to set point, involved in weight control. They explore the importance of genetics and psychological predisposition, as well as the contribution of the environment in sabotaging weight loss efforts, the importance of exercise and sleep, and the relevance of circadian rhythms to weight. They also review some of the most popular diets, including the significance of calories, as well as the psychotherapeutic, pharmacological, and surgical options that are currently available for the overweight and obese.
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